How often should you do PRP Microneedling?

How often should you do PRP Microneedling? 

Wondering how often should you do PRP microneedling? You’re not alone. It’s one of the most common questions we hear, and the answer isn’t as simple as picking a number on a calendar.

In this article, we’re sharing the same guidance Ashley, a Certified Family Nurse Practitioner (FNP-C) and the founder of Luxe Aesthetics Jax, gives her clients every day.

We’ll walk through questions like Can I do PRP every 2 weeks? and Can you do PRP too often?, and explain what actually makes sense for your skin. Let’s get into it.

About How Often Should You Do PRP Microneedling

One thing we like to clarify early is what you’re actually seeing after a PRP microneedling session. In the short term, PRP microneedling can create a noticeable glow or plumping effect. 

That fresh, radiant look often comes from mild inflammation and very superficial swelling, which is a normal part of the skin’s healing response. It can look great, but it’s temporary. That initial radiance isn’t the same thing as collagen remodeling.

The real changes people are hoping for, improved texture, firmer skin, softer lines, happen deeper in the skin and take time. Collagen regeneration follows a biological timeline. Your body needs weeks, not days, to produce and organize new collagen in a meaningful way. 

This is why frequency matters so much. Trying to rush treatments doesn’t speed up results. It can actually stress the skin and interfere with proper healing.

From both clinical experience and medical literature, PRP microneedling is typically recommended as a series of treatments rather than something done constantly.

We suggest around three to six sessions, usually spaced about four to six weeks apart. This aligns with how long collagen remodeling actually takes and gives the skin time to fully heal before the next treatment.

Microneedling With PRP: How It Works

PRP might feel like a modern beauty treatment, but it actually comes from regenerative medicine. Long before it showed up in aesthetics, doctors used PRP in orthopedics and sports medicine to help the body heal injured tissue. 

That same healing principle is what makes it valuable for skin.

When you do PRP microneedling, a small amount of your own blood is processed to concentrate platelet-rich plasma. This plasma contains growth factors, which act as messengers in your body. They tell your skin where to repair, rebuild, and regenerate.

As microneedling creates controlled stimulation in the skin, those growth factors support the healing process that follows and stimulate collagen production in the dermal layer.

When PRP is paired with microneedling, the focus is on healing quality rather than quick results. 

It All Depends on Your Goals

How often you should do PRP microneedling really comes down to what you’re treating, not just the procedure itself. 

The skin doesn’t heal the same way everywhere on the face. The right treatment schedule depends on both the area being treated and how your skin responds to healing.

Some areas of the face regenerate more quickly, while others need more time and a gentler approach. Here’s how to tell based on your goal:

To Remove Under-Eye Circles

To treat under eye circles, we like to slow things down and get very intentional. The skin under your eyes is thin and delicate, so it doesn’t respond well to being pushed too hard or too often.

PRP can be a great option here, especially if dark circles are something you’ve always had and filler isn’t the right fit for you. But this isn’t a one-and-done situation. 

Real improvement usually comes from a series of treatments, spaced conservatively, often about once a month, so your skin has time to heal and regenerate between sessions.

Doing PRP too frequently in this area can lead to irritation or prolonged swelling. The opposite of what you want under the eyes. 

When we keep the frequency thoughtful and measured, PRP can support better skin quality in a way that looks natural and refreshed.

Recommended frequency

Initial series: Every 4–6 weeks
Typical series: 2–4 sessions

Fine Lines Around the Mouth

This is one of the more challenging areas to treat, and we see it often. The skin here moves constantly when you talk, smile, and eat, which affects how collagen rebuilds and why results tend to take more time.

In our experience, PRP paired with microneedling works best when the focus is on supporting collagen production gradually. This area also responds well to a thoughtful approach that allows the skin to strengthen over time.

What makes the biggest difference here is consistency, not aggressive frequency. 

Treating too often around the mouth can irritate the skin and disrupt healing, especially in such a high-movement area. When sessions are spaced appropriately, the improvements tend to look softer, more natural, and more refined.

Recommended frequency

Initial series: Every 4–6 weeks
Typical series: 3–4 sessions

For Overall Skin Texture and Tone

If what you’re really after is better overall skin quality, smoother texture, more even tone, skin that looks healthier and more resilient, collagen is at the center of that conversation. When we’re younger, our bodies replenish collagen and elastin easily. 

As we move through our mid-twenties and beyond, that process naturally slows. PRP microneedling is designed to support your skin’s natural repair process rather than force quick change. 

In our experience, focusing on collagen health leads to more noticeable improvements in texture and tone over time, especially when treatments are spaced properly.

Microneedling is known to improve uneven texture and tone by stimulating collagen, and PRP can help support how well the skin heals and responds. 

Recommended frequency

Initial series: Every 4–6 weeks
Typical series: 2–3 sessions

For Acne Scars or Textural Irregularities

Acne scars form when collagen doesn’t rebuild evenly as the skin heals, which is why you’re left with indentations or rough texture instead of a smooth surface.

This is where PRP microneedling can be helpful, but only when it’s approached with patience. We’re not trying to correct scars overnight. The goal is to support collagen signaling over time so your skin can slowly rebuild structure. 

Giving your skin enough time between sessions is essential here, because real dermal remodeling can’t be rushed. In practice, when we space treatments properly, results tend to look more natural and consistent, rather than forced or overdone.

Recommended frequency

Initial series: Every 4–6 weeks   

Typical series: 3–6 sessions

Maintenance vs Corrective Treatments

This is usually where the big questions come up: ‘How often should you do PRP microneedling?’ and ‘Can you do PRP too often?’. And the honest answer is that more frequent isn’t better.

We typically think about PRP microneedling in two phases to set clear expectations and keeps the skin healthy long term.

  1. Corrective Phase

The corrective phase focuses on stimulating collagen to address a specific concern, whether that’s texture, fine lines, or scarring. 

We provide these treatments in a series, with enough time between sessions for your skin to heal and rebuild properly. This spacing is essential because collagen regeneration takes weeks, not days.

  1. Maintenance Phase

Once you’ve reached your initial goal, this is where we ease into maintenance. At this stage, the focus shifts to supporting your skin’s health and longevity. Treatments are spaced further apart so your results can be preserved and your skin has time to stay balanced and resilient.

If you try to do PRP every couple of weeks, you may actually work against your skin. Stimulating it again before it’s ready can increase irritation and slow progress instead of improving it.

Recommended frequency: 1-2 times a year

Final Thoughts on Frequency of Microneedling With PRP

Hopefully this article helped answer how often should you do PRP microneedling and made it clear that frequency really depends on your specific goals. More than anything, your skin needs enough time to recover, regenerate, and produce new collagen in a healthy way.

Because of this, consistently spaced treatments tend to work better in the long run, and they often save you from doing more than your skin actually needs. If you’re curious to learn more about all things microneedling with PRP recovery, we have an article on that too. 

If you’re ready to start your journey with PRP microneedling and you’re in Jacksonville, Florida, we’d love to welcome you in for a complimentary consultation. 

Our founder and lead provider, Ashley, will sit down with you, talk through your goals, and create a thoughtful plan tailored specifically to your skin.

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Microneedling And Acne: 5 Things You Should Know